1 - 10 of 46 articles
This exploratory recursive partitioning analysis modeled associations between prespecified covariates and survival outcomes using pooled data from 4 randomized clinical trials of adult patients with BRAF V600–mutated metastatic melanoma treated with dacarbazine, vemurafenib, or cobimetinib plus...
Key PointsQuestionCan next-generation sequencing reveal potentially actionable alterations in a significant proportion of patients with soft-tissue sarcoma?
FindingsIn this analysis of next-generation sequencing data from 584 patients, actionable genomic alterations in up to 41% of cases were...
This narrative review discusses the pathophysiology of adult acute lymphoblastic leukemia and recent progress in the development of personalized therapies.
This Viewpoint discusses how expert review of breast pathology in borderline lesions may offer the opportunity to reduce overdiagnosis and overtreatment of breast cancer.
This secondary analysis of the NRG Oncology/RTOG 0424 randomized clinical trial examines the proportion of patients with MGMT promoter methylation and its association with survival outcomes in high-risk glioma treated with radiotherapy and temozolomide.
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