1 - 10 of 32 articles
This commentary discusses the findings of a randomized clinical trial of trastuzumab vs a biosimilar in patients with metastatic breast cancer that was published in JAMA and posits 3 questions for consideration moving forward in the development and clinical use of biosimilars.
This Viewpoint argues that surgery is not necessary for all patients with rectal cancer who respond to chemoradiation.
This secondary analysis of a National Cancer Institute of Canada trial investigates quality of life at days 10 and 42 after radiotherapy with a bone metastases–specific quality-of-life tool.
This Viewpoint discusses overall survival in cancer trials as a surrogate end point for real-world patients.
This Viewpoint argues that that it is premature to practice selective withdrawal of surgery based on the curative contribution of surgery, the lack of reliable predictive biomarkers, and the scarcity of solid evidence in support of this practice.
This case-control study assesses the association of cytotoxic, anti-inflammatory, and immunomodulating agents with the risk for developing myeloid neoplasms among patients with autoimmune disease.
ImportanceMultiple myeloma (MM) is the second most common hematological malignant abnormality. The introduction of immunomodulatory drugs (IMiDs) and proteasome inhibitors (PIs) has greatly improved the overall survival of patients with MM. Prevention and treatment of cardiovascular and...
Key PointsQuestionDoes the tumor immune microenvironment differ between HIV-positive and HIV-negative patients with anal squamous cell carcinoma (SCC)?
FindingsIn this study of 40 tumor specimens from patients with anal SCC, there were no significant differences in programmed death-ligand 1...
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