1 - 10 of 29 articles
Key PointsQuestionWhat is the effect of molecular alterations on survival of patients with non–small-cell lung cancer and brain metastases?
FindingsIn this database analysis, in addition to previously known prognostic factors, EGFR and ALK gene alterations of the original primary lung tumor were...
Using data from a prostate cancer registry, this study correlated HSD3B1 genotype with response to androgen-deprivation therapy in patients with prostate cancer.
Key PointsQuestionDoes integration of capecitabine into a taxane- and anthracycline-containing chemotherapy regimen improve survival as adjuvant treatment of early breast cancer?
FindingsIn the FinXX trial, patients randomly allocated to receive a capecitabine-containing regimen did not survive...
This Viewpoint examines the use of assays that allow for genetic analyses of plasma cell-free DNA in patients with cancer.
Key PointsQuestionWhat is the effect of human papillomavirus (HPV) vaccination on cervical intraepithelial neoplasia (CIN) rates when adjusting for cervical cancer screening?
FindingsIn this population-based registry study, after adjustment for changes in screening across 2007 to 2014,...
This commentary discusses lessons learned from a trial published in JAMA that reported no difference in survival between chemoradiotherapy vs chemotherapy alone in patients with locally advanced unresectable pancreatic cancer.
ImportanceLung cancer is the leading cause of cancer death in the United States in all ethnic and racial groups. The overall death rate from lung cancer is higher in black patients than in white patients.
ObjectiveTo compare the prevalence and types of somatic alterations between lung cancers...
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