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This commentary discusses a trial published in JAMA that compared the effects of chest tube size and analgesia types on pain and efficacy of pleurodesis for management of malignant pleural effusion.
This Viewpoint argues against a continued role for intermittent androgen-deprivation therapy in the management of men with prostate cancer.
This genomic profiling study investigates the genomic mechanisms underpinning resistance to the androgen receptor antagonist enzalutamide in metastatic castration-resistant prostate cancer.
This Viewpoint highlights recent findings in the treatment of central nervous system tumors.
ImportancePatients given systemic treatment for testicular germ cell cancer (GCC) are at increased risk for a second malignant neoplasm (SMN). Previous studies on SMN and causes of death lacked information on the exact treatment applied or were based on patients receiving former treatment...
ImportanceEfficacious ERBB2 (formerly HER2 or HER2/neu)-directed treatments, in addition to trastuzumab and lapatinib, are needed.
ObjectiveTo determine whether neratinib, an irreversible pan-ERBB tyrosine kinase inhibitor, plus paclitaxel improves progression-free survival compared with...
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