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Key PointsQuestionDoes the use of a biomarker to select patients in phase 1 trials improve efficacy outcomes?
FindingsThe meta-analysis of 346 phase 1 trial including 13 203 patients found that using a biomarker-based selection strategy was associated with improved response rate (median, 30.6%...
Key PointsQuestionWhat is the efficacy of 2 types of self-administered acupressure compared with usual care for treating chronic fatigue, poor sleep, and low quality of life in fatigued breast cancer survivors?
FindingsIn this randomized clinical trial that included 288 breast cancer survivors,...
This meta-analysis summarizes published estimates of the association between extent of glioblastoma multiforme resection and overall and progression-free survival.
This Viewpoint summarizes recent findings on optimizing adjuvant chemotherapy and surgery for early- and late-stage breast cancer.
This systematic review and meta-analysis evaluates the effect of neoadjuvant endocrine therapy on response rate and the rate of breast conservation surgery for estrogen receptor–positive breast cancer.
This Viewpoint argues in favor of cancer-related, direct-to-consumer advertising of prescription drugs.
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