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This investigation of recent news coverage of cancer research found that although most new cancer drugs offer only modest benefits, they are often described in the news media with superlatives, such as “revolutionary” and “game changer,” that may be unwarranted.
This Viewpoint suggests ways to add efficiency to cancer research, including decreased costs as an explicit goal of clinical trials, data sharing, and enhanced accountability for cancer research dollars.
ImportanceMetastatic squamous non–small-cell lung cancer (SQ NSCLC) is a serious and life-threatening malignant condition with unmet medical need. In late December 2014, the US Food and Drug Administration (FDA) obtained the data monitoring committee report of a planned interim analysis of a...
ImportanceEvolving data on the effectiveness of postmastectomy radiation therapy (PMRT) have led to changes in National Comprehensive Cancer Network (NCCN) recommendations, counseling clinicians to “strongly consider” PMRT for patients with breast cancer with tumors 5 cm or smaller and 1 to 3...
This Viewpoint highlights the role of next-generation sequencing in the rapid emergence of new cancer therapies as well as the challenges of safely regulating these therapies without unnecessarily delaying their implementation.
Abstract Importance Chemotherapy may result in a detrimental effect on ovarian function and fertility in premenopausal women undergoing treatment for early-stage breast cancer (EBC). To minimize risk of harm to ovarian function and fertility for patients in this setting, careful considerations...
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