1 - 10 of 34 articles
ImportanceOptimal chemotherapy dosing in obese patients remains uncertain, with variation in practice. Dose reduction strategies are often used to avoid chemotoxicity, but recent American Society of Clinical Oncology guidelines recommend full dose.
ObjectiveTo evaluate the impact of body mass...
ImportanceAlthough many patients with end-stage cancer are offered chemotherapy to improve quality of life (QOL), the association between chemotherapy and QOL amid progressive metastatic disease has not been well-studied. American Society for Clinical Oncology guidelines recommend palliative...
This Viewpoint discusses 3 principles of behavioral psychology that provide insight into how patients’ treatment preferences are influenced in serious illnesses.
ImportanceBody fat increases postmenopausal breast cancer risk. Physical activity may decrease risk through adiposity changes, but the optimal dose of activity is unknown.
ObjectiveTo compare the effects of 300 vs 150 min/wk of moderate to vigorous aerobic exercise on body fat in postmenopausal...
ImportancePatients with resectable gastrointestinal stromal tumors (GISTs) might not receive the recommended duration of adjuvant therapy if their risk of recurrence is underestimated, which can have an impact on their recurrence-free survival (RFS).
ObjectiveTo determine the extent of physician...
This case report describes the first use of vemurafenib in an infant with BRAF V600E–mutated Langerhans cell histiocytosis, showing improvement in the patient’s general health and eventual complete remission.
This Viewpoint reviews the convergence of evidence in support of adjuvant chemotherapy for bladder cancer and proposes that despite the lack of level 1 evidence it is time for perioperative chemotherapy for bladder cancer (neoadjuvant or adjuvant) to become standard of care.
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