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BackgroundWhile administrative databases are used to assess general indicators of quality of care, a detailed audit of the process of clinical care usually requires review of hospital medical records.ObjectiveTo evaluate the feasibility of assessing the management of severe hypokalemia using...
BackgroundA carbose is the first of a new class of antidiabetic agents, the α-glucosidase inhibitors.This study characterizes and identifies predictors of persistence of use of acarbose.MethodsMedical, pharmaceutical, and demographic records were extracted for 2 cohorts of patients (social...
ObjectiveTo test the efficacy of individualized stress management for primary hypertension in a randomized clinical trial with the use of ambulatory blood pressure (BP) measures.MethodsMen and women aged 28 to 75 years with mean ambulatory BP greater than140/90 mm Hg received 10 hours of...
BackgroundStudies of oral contraceptives (OCs) containing 50 µg or more of estrogen suggest an increased risk of myocardial infarction (MI) among current users, particularly if they smoke heavily.ObjectiveTo assess whether use of the newer lower-dose OCs increases the risk of MI.MethodsA...
Venous thrombosis is a cause of considerable morbidity and is often responsible for chronic venous disorders that frequently lead to visits to dermatologists and others involved in wound healing. Over the past several years, many new causes of thrombophilia have been identified and have...
BackgroundBecause the value of popular forms of alternative care for chronic back pain remains uncertain, we compared the effectiveness of acupuncture, therapeutic massage, and self-care education for persistent back pain.MethodsWe randomized 262 patients aged 20 to 70 years who had persistent...
BackgroundUse of anticholinergic (ACH) medications is a biologically plausible and potentially modifiable risk factor of delirium, but research findings are conflicting regarding its association with delirium.ObjectivesTo evaluate the longitudinal association between use of ACH medications and...
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