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BackgroundThe control of hyperglycemia is of major importance in the treatment of patients with type 1 diabetes mellitus. However, there is no consensus about the required degree of metabolic control in patients with type 2 diabetes mellitus and about the role of hyperglycemia in diabetic...
BackgroundTo determine whether there are sex differences in the demographics, treatment, and outcome of patients with acute myocardial infarction in the United States, data from the National Registry of Myocardial Infarction-I from September 1990 to September 1994 were examined.MethodsThe...
Septic shock resulting from Mycobacterium tuberculosis(TB) occurs only rarely, even among patients infected with human immunodeficiency virus. We report a case of fulminant TB sepsis in the setting of human immunodeficiency virus infection. This case illustrates the hazards of corticosteroid use...
ObjectiveTo evaluate the impact of sumatriptan succinate injection compared with placebo on productivity loss during a migraine attack in the workplace.DesignRandomized, double-blind, placebo-controlled, parallel-group clinical trial.SettingFifteen clinical centers in the United...
BackgroundDonepezil hydrochloride (Aricept) is a selective acetylcholinesterase inhibitor developed for the treatment of Alzheimer disease. This phase 3 study was 1 of 2 pivotal trials undertaken to establish the efficacy and safety of using donepezil in patients with mild to moderately severe...
ObjectiveTo explore the relationship between general internists' tendency to conserve medical resources and their willingness to participate in physician-assisted suicide (PAS).Design and ParticipantsSurvey of a random sample of general internists in 6 urban areas of the United...
ObjectiveTo provide recommendations for the treatment of acquired immunodeficiency syndrome–related cytomegalovirus (CMV) end-organ diseases, including retinitis, colitis, pneumonitis, and neurologic diseases.ParticipantsA 17-member panel of physicians with expertise in clinical and virological...
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