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Summary A quantitative comparison has been carried out between laser scanning confocal microscopy on living cells and standard electron microscope methods on fixed samples. It was estimated from these measurements that there was about 10––20% reduction in thickness in fixed samples of...
Summary Gas chromatography––mass spectrometry with selected-ion monitoring was used to measure the yields of radiation-induced base products in aqueous solutions of native or heat-denatured DNA irradiated in the dose range 20––100 Gy. These DNA solutions were saturated with nitrous oxide,...
Summary Radon and its progeny, which emit αα-particles during decay, may play an important role in inducing human lung cancer. To gain a better understanding of the biological effects of αα-particles in human lung we studied the response of cultured human airway epithelial cells to X-rays and...
Summary Mouse kidneys were bilaterally irradiated with fractionated doses of 15 ×× 1··2 Gy, 15 ×× 1··6 Gy or 15 ×× 2··0 Gy. After an interval of 26 weeks the mice were re-irradiated with a range of single doses and functional kidney damage was measured (from clearance of ( 51 Cr)EDTA)...
Summary This work relates to studies on modes of phototoxicity by sulphonated meso-tetraphenylporphines on cultured cells. Toxicity appears to be related to inhibition of microtubule function. Treatment of human cervix carcinoma cells of the line NHIK 3025 incubated for 18 h with...
Summary We have recently demonstrated by dielectric relaxation studies in the radio-frequency range that there is a sharp decrease in the conductivity and permittivity of the membranes of chick embryo myoblasts in vitro at the time of fusion (60 h) (Bonincontro et al. 1987). This sharp fall in...
Summary Recent data suggest that the differences in radiosensitivity between cell lines can be related to differences in dsb induction (Radford 1986a). In the light of this we have set out to assess the extent to which differences in radiation survival between human tumour cell lines can be...
Summary ESR spectroscopy was used to study free radicals in an irradiated single crystal of thymine monohydrate at 77 K. At low microwave power (20 µµW), a broad doublet is found to be super-imposed on the well known resonance patterns of the 5-yl and 7-yl radicals. The doublet spectrum has...
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