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Summary This paper extends our earlier observations on the effects of the sulphydryl (SH)-containing compound dithiotheitol (DTT) on the radiation response of Bacillus subtilis transforming DNA to three other SH-containing compounds–cysteamine, cysteine and glutathione (GSH). In general, all...
Summary This study was designed to measure the effect of aerosol particle size on the deposition, retention, excretion and translocation of 239 Pu inhaled as the dioxide by Beagle dogs. To address these questions, young adult male and female Beagle dogs received single brief inhalation exposures...
Summary The effects of chronic γ-irradiation on the gonads of adult Ameca splendens (Osteichthyes: Teleostei) have been investigated at a mean dose rate of 7·3 mGy hour −1 for 5–244 days. Spermatogenesis was disrupted after an accumulated dose of 0·95 Gy (5 days exposure) and after 52 days...
Summary Exponentially growing cells of an established line derived from a mouse osteosarcoma (MOS) have been studied by time-lapse cinematography after irradiation with 3 Gy of 200 kV X- rays or 1·5 Gy of 14 MeV neutrons. Cell cycle times (T c ) of individual cells and their progeny in three...
Summary Studies on X-ray sensitive mutants of Saccharomyces cerevisiae (Benathen 1973, Benathen and Beam 1977) show that the XS6, XS8 and XS9 genes are not only involved in the repair of X-ray-induced damage but also in the repair of U.V.-induced damage. Analysis of the U.V. sensitivity of...
Summary The absolute rate for the repair reaction of radiation-induced, oxygen-dependent lesions in bacterial transforming DNA with the sulphydryl (SH)-containing compound dithiothreitol (DTT) has been determined using a fast response method, the gas explosion technique, to be 1·6 × 10 6 dm 3...
Summary The uptake of reducing equivalents of ·CO − 2 by lumichrome in spectrophotometric titrations has been re-examined in the light of a recently reported extinction coefficient of 10 500 M −1 cm −1 at pH 6, which is in agreement with 10 270 ± 100 M −1 cm −1 determined here. The...
Summary The induction and rejoining of DNA strand breaks after γ-irradiation in three goldfish ( Carassius auratus ) cell lines with different sensitivities to the lethal effect of γ-rays has been studied by the DNA strand separation method using hydroxylapatite chromatography. The induction...
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