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Summary The rate of development of post-irradiation oxygen-dependent damage when oxygen is available, and its rate of elimination when seeds are first post-hydrated in oxygen-free water prior to their transfer to oxygenated water, was studied in barley seeds of ∼3 per cent, ∼8 per cent and...
Summary The induction of inactivation and mutation to thioguanine-resistance in cultured human diploid fibroblasts was studied after exposure to ionising radiations with LETs in the range 20–470keV µm −1 . Unique r.b.e. values were obtained for inactivation and mutation induction with nine...
Summary Inactivation and mutation to thioguanine-resistance of V79 hamster cells were studied after irradiation with accelerated helium, boron or nitrogen ions covering a range of linear energy transfer from 28 to 470 keV µm −1 . For all radiation qualities a dose-dependent increase in mutant...
Summary L929 cells were irradiated by cyclotron-produced neutrons and by 14·8 MeV monoenergetic neutrons. For comparison cells were also irradiated by 60 Co gamma rays. Following irradiation cells were treated by an equimolar solution of deoxyribonucleosides, and the effect on cell survival...
Summary Carbon K characteristic ultrasoft X-rays of energy 0·278 keV were found to be effective in inducing inactivation and mutation to thioguanine resistance in cultured V79 Chinese hamster cells and human diploid fibroblasts. These X-rays act as a probe of the sensitive sites within the cells...
Summary This paper, which is the first of four covering the inactivation of clonogenic capacity and induction of mutation in cultured mammalian cells, deals briefly with the general aims of the work and describes the irradiation techniques used. Human diploid fibroblasts and V79 Chinese hamster...
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