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Summary In rat-liver t-RNA γ-irradiated in dilute aqueous solution, structural changes are revealed by polyacrylamide gel electrophoresis. A new, fast-moving and non-dialysable component appears, the relative amount of which is a function of both the radiation dose and t-RNA concentration during...
Summary The coliphage T7 was x-irradiated in the presence and absence of ethanol, an effective ·OH and ·H scavenger, in buffered suspensions saturated with N 2 , N 2 O and O 2 . In 10 −3 × dilution of the original suspending organic medium, ethanol was protective in all three experimental...
Summary The addition of alcohols (methanol, ethanol, t-butanol, ethylene glycol, and glycerol), SH compounds (cysteamine, cysteine and mercaptoethanol) and cystamine protected DNA molecules of mammalian cells from radiation-induced single-strand scissions. The protection afforded with these...
Summary The formation and stabilization of free radicals in x-irradiated sulphur and selenium amino acids have been investigated by electron paramagnetic resonace (E.P.R.). An attempt has been made to identify the main radical species present. It is shown that selenium compounds have lower...
Summary Primary root meristems of Pisum sativum with a mitotic cycle prolonged to ∼36 hours by lowering the temperature to 10°c, exhibited complete mitotic inhibition after 3 days of exposure to gamma-radiation at a rate of 0·83 R/min. 3 H-thymidine autoradiography, 3 H and 14 C...
Summary The radiation response of a long-term culture of human immunoglobulin-producing lymphoid cells (T 1 cells) studied by the colony-forming method, is remarkably similar to the response of other mammalian cell cultures. The relevant parameters are: n = 7–8; D q = 175 rads and D 0 = 85...
Summary Timed-pregnancy rats were exposed on gestation day 13 to single doses of gamma ( 60 Co)-irradiation of from 25 to 200 R in increments of 25 R, and to split doses of 100 R plus a second dose of from 25 to 150 R in increments of 25 R, with a 9-hour interval between exposures. Additional...
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