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INTRODUCTION: To determine the incidence of treatment-induced sexual dysfunction in depressed outpatients treated with five different antidepressants. METHODS: 100 depressed patients (ICD-10 criteria for depressive episode, recurrent depressive disorder, and dysthymia) with an active sex life...
INTRODUCTION: Fifty-three patients admitted to a psychiatric inpatient unit in South London were interviewed to ascertain their satisfaction with services provided for them. METHOD: The level of satisfaction with various aspects of treatment was evaluated using a 45-item questionnaire. RESULTS:...
Current biological approaches to the treatment of depression focus mainly on modification of monoaminergic neurotransmission. New agents targeting these neurotransmitters are under development. Many novel antidepressant targets are however under investigation. These include the neurokinins,...
A contemporary of Emil Kraepelin, Oskar Panizza was a psychiatric trainee under Bernhard von Gudden at the Oberbayerische Kreisirrenanstalt München. While participating in Gudden's famous degeneration studies, Panizza became psychotic. He quit his job and became a writer, trying to cope with...
This paper presents the case of Herb Kern, the first patient with clear-cut seasonal mood cycles in whom light therapy was used to reverse depression. His successful treatment was an inspiration to the author to define the syndrome of Seasonal Affective Disorder (SAD) and use light therapy as a...
This report describes a case of manic symptoms induced by olanzapine in an 85-year-old female with a 3 year history of delusional disorder. She was treated in the past with trifluoperazine and risperidone. Symptoms were severe enough to require detention in hospital. Florid manic symptoms...
INTRODUCTION: Quetiapine (Seroquel TM ) is an atypical antipsychoticdrug with demonstrated efficacy and tolerability. In particular, placebo-level extrapyramidal symptoms (EPS) across the entire dose range and a low propensity to cause sexual dysfunction suggest it may be associated with greater...
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