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A derivative of chitooligosaccharide (COS) with quaternary ammonium functionality was synthesized and characterized by means of FT-IR and NMR spectroscopy. Its amtimicrobial activity was evaluated against Streptococcus mutans , which is a principal etiological agent of dental caries in humans....
Poly(ethylene glycol)-grafted poly(3-hydroxyundecenoate) (PEG- g -PHU) networks were prepared by irradiating homogeneous solutions of poly(3-hydroxyundecenoate) (PHU) and the monoacrylate of poly(ethylene glycol) (PEG) with UV light. The resulting polymer networks were characterized by measuring...
Silk sericin (SS) possessing moisture-retaining property was reacted with activated poly(ethylene glycol) (PEG) to obtain self-assembled SS nanoparticles. The aliphatic and aromatic hydroxyl groups of serine and tyrosine residues as the reaction sites in SS were clarified by amino acid analysis...
Guanidine hydrochloride (GdnHCl)-induced unfolding of human prostatic acid phosphatase (hPAP), a homodimer of 50 kDa subunit molecular weight, was investigated with activity measurements, size exclusion HPLC, tryptophan fluorescence, 1-anilinonaphtalene-8-sulfonate (ANS) binding and reactivity...
Protein aggregation is involved in a number of disorders, such as Alzheimer’s disease, cystic fibrosis, and prion diseases. Such aggregates are formed by peptides in β-conformation. The study of the processes of aggregation or its inhibition makes it necessary for the peptide to remain in a...
Fourier transform infrared (FTIR) spectroscopy was used to investigate the secondary structure of pediocin PA-1 in different aqueous media in relation to its antimicrobial activity. The experiments were performed at pD (pH meter corrected for deuterium isotope effect) 6, 7, and 8 and during a...
The polymeric basis for the mechanical properties of primary plant cell walls has been investigated by forming analogous composites based on fermentation of the bacterium Acetobacter xylinus , either alone or in the presence of xyloglucan or pectin. Simultaneous small-angle X-ray scattering and...
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