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Analytical gradient polyacrylamide gel electrophoresis of antigens from Mycobacterium tuberculosis H 37 RV was combined with crossed line Immunoelectrophoresis to locate the position of antigens in polyacrylamide gel columns that appeared to be specific for M. tuberculosis H 37 RV. Specificity...
It has been reported that in the absence of antibody, Clq or C I will bind to human T and B lymphocytes, lymphoblastoid cell lines and platelets. Since the binding of Clq is reported to occur independently of both the Fc receptor and membrane surfaces incorporating beta 2 microglobulin, the...
A unique regulatory mechanism has been proposed for ganglioside which functions in immune responses to temporarily restrain B lymphocytes of all specificities and at various levels of differentiation. Utilizing antigen competition protocols, experiments were designed to exploit and extend the...
Total hemolytic complement activity (CH 50 ) was compared in sera from normal and tumor-bearing hamsters. CH 50 ranged from 160 to 216 in normal animals and from 82 to 152 in tumor-bearing animals. Preliminary screening assays indicated that of 9 complement components assayed, only C2 and C4...
Two-Week-old A/J mice were placed on diets containing either adequate or inadequate amounts of zinc. Because of the difficulties encountered in working with mice of this age, it was not possible to include a pair-fed control to assess the degree of inanition accompanying the deficiency in zinc....
Mice were challenged with high (10 8 ) or low (10 4 ) numbers of allogeneic tumor cells and assessed for cellular immunity. The responses obtained indicated that high dose challenge produced both delayed-type hypersensitivity (DTH) and cell-mediated cytotoxic reactivity (DCMC), while low dose...
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