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BACKGROUND: Seasonal variations of reproductive functions in wild mammals are well known. Similar but blunted seasonal trends have also been described for humans. METHODS: We performed a questionnaire‐based study of 149 patients that was designed to search for environmental influence on symptom...
BACKGROUND: Intercourse in mammals is often coordinated with ovulation, for example through fluctuations in libido or by the acceleration of ovulation with intercourse. Such coordination has not been established in humans. We explored this possibility by examining patterns of sexual intercourse...
BACKGROUND: The purpose of this study was to determine the effect of progestin, relaxin (RLX) and transforming growth factor β1 (TGFβ1) on the content of relaxin receptor (LGR7) mRNA. The effect of RLX on insulin‐like growth factor binding protein‐1 (IGFBP‐1) production was determined to...
BACKGROUND: To examine the effect of in utero exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) on age at menarche in offspring, we conducted a cohort study over two generations. METHODS: Female participants (and their offspring) in a Michigan angler cohort...
We report our attempts to achieve a successful pregnancy outcome with calcium ionophore A23187 and puromycin oocyte activation using sperm from a normozoospermic husband of a patient with previous repeated failed fertilization following ICSI. Oocytes from the female partner of a couple with a 4...
BACKGROUND:The precise mechanism of uterine prolapse is poorly understood. This immunohistochemical study was performed on paraffin‐embedded sections of the cardinal ligaments in an attempt to evaluate the differential expression of gonadal steroid receptors in human cardinal ligaments of...
BACKGROUND: Oocyte donation is a popular treatment option among women with ovarian dysfunction. Little is known about the amount of information recipients have about their donors and if the amount of information the couple has relates to their plans to disclose. The purpose of this study was to...
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