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Thirty cases of ductal carcinoma in situ (DCIS) of the breast, showing histological microcalcifications, were studied to clarify their mechanism of formation. Undecalcified sections revealed three types of calcium precipitates: type I and II granular calcifications (GCs) and laminar...
The mitotic index (MI) is the most commonly used quantitative measure in anatomic pathology but has been widely criticized for supposed “irreproducibility.” In this article, the authors show that mitotic figure (MF) counts may be described by a Poisson distribution, give confidence intervals...
Limited information is currently available on the molecular and immunophenogenotypic characteristics of CD30-positive anaplastic large cell (ALC) lymphomas occurring in human immunodeficiency virus (HIV)—infected individuals. To address this issue, the authors have undertaken a combined...
Posttransplant lymphoproliferative disorders (PTLD) are related to Epstein-Barr virus (EBV) and range from lymphoid hyperplasias to lymphomas. The authors report 11 transplant recipients with recurrent EBV-associated lesions. Four patients presented with EBV-positive mononucleosis-like...
Although several morphological and molecular genetic studies have implicated various grades of pancreatic duct hyperplasia as precursor lesions to infiltrating pancreatic adenocarcinoma, the identity of preinvasive pancreatic neoplasms remains controversial. In the present study, the authors...
We describe a case of a novel soft tissue neoplasm, composed of a monotonous population of cells. Their cytoplasm was packed with mitochondria, and had no inununohistochemical or ultrastructural evidence of differentiation. The neoplasm, located within the thigh of a 50-year-old man, was...
The coexistence of mucinous ovarian and appendiceal tumors in association with pseudomyxoma peritonei (PP) is well established. However, it has not been determined whether they represent independent or metastatic neoplasms. The authors analyzed microsatellites on chromosome 17q 21.3–22 (nm23),...
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