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The herbicide, paraquat is highly toxic for mammals, with the lungs being the main target organ, because of the active accumulation of the compound in this organ. The cellular toxicity of paraquat has been shown to be an O 2 -driven process and hyperoxia is known to increase the lethality of...
1 NK and T cell functions were measured in peripheral blood lymphocytes of workers occupationally exposed to lead. 2 No differences were found in these functions even in those workers with higher levels of blood and urine lead and urinary δ-ALA than the currently accepted biological limit values...
1 Members of the British Toxicology Society partici pated in a survey to determine their attitudes, beliefs, and perceptions regarding risks from chemicals. Similar surveys had previously been conducted with toxicologists and members of the general public in the United States and Canada. Data...
In this work we have studied the respiratory burst and chemotaxis of polymorphonuclear leukocytes from 51 workers exposed to chlorinated compounds, which were compared with those of non-exposed, age- and sex- matched invididuals. These two neutrophil functions were significantly reduced as...
Trichloroethylene (TCE) was exposed in the presence of the spin trap N- tert -butyl-α-phenyl nitrone (PBN, 0.1 M) to ionizing radiation from two different sources in an attempt to determine the origin of the spin-trapped radicals generating the EPR spectra in precision cut liver slices. TCE...
1 Rifampicin (RMP) induced hepatic injury was investi gated in growing rats. The interaction of moderate and severe protein-energy malnutrition (PEM) was also investigated. 2 Status of oxidative/antioxidative profile was studied by the mechanistic approach, to enumerate the nature of injury. 3...
1 The effect of Egyptian cobra (Naja haje) venom on the normal electrical activity of the cardiac muscles (ECG) and arterial blood pressure of envenomated rats were investigated in this study. 2 Rats were divided into three groups. The first group was injected im with saline and considered as...
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