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Wilson disease (WD) is an inherited disorder of copper metabolism that affects the brain, liver, and other organs. Our group recently reported close linkage between the locus for WD and a polymorphic red cell enzyme, esterase D (EsD), in a large inbred Israeli‐Arab lineage. We have subsequently...
In an earlier paper, positive but nonsignificant lod scores were found in pair‐wise linkage tests between multiple endocrine neoplasia type 2A (MEN‐2A) and both the haptoglobin (HP) locus on chromosome 16 and group‐specific component (GC) locus on chromosome 4. Recently discovered...
Two distinct patterns of somatization were identified in 807 Swedish adopted men, using comprehensive lifetime psychiatric and sick‐leave records. “Diversiform” somatizers had a high frequency of brief sickness occasions for a wide diversity of complaints, particularly pain in the head,...
Parotid saliva contains a variety of proline‐rich proteins. This study found that, among 306 children between the ages of 5 to 15 years, there is a significant increase in the decayed‐missing‐filled tooth surface (DMFS) score of the permanent teeth with age in children with the specific...
An approach is outlined for the analysis of nonrandom allelic associations in multilocus systems in a diploid population. The concept of composite link functions in generalised linear model analysis is used to handle the problem of incomplete identification of constituent gametes often...
The genetic and environmental antecedents of clinically distinct disorders leading to somatization were compared in 807 Swedish men and 859 Swedish women adopted at an early age by non‐relatives. Asthenic somatization, the predominant form in men, was a neurotic disorder associated with a lower...
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