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There is much concern about the increasing presence in the environment of synthetic chemicals that are able to disrupt the endocrine system. Among these compounds, 4-nonylphenol (4-NP) is one of the most studied xenoestrogens, due to its widespread accumulation in water sediment and consequent...
Helix pomatia ( Hp ) juice is a common enzymatic preparation for deconjugation of urinary steroids. It has been used in many published studies on urinary testosterone (T) in chimpanzees and bonobos, although the ability of Hp juice to convert other urinary steroids into T has been reported for...
It is widely believed that female birds strategically allocate androgens to yolk in the manner that best equips offspring for feeding conditions during their development. Because most avian studies have focused on multi-egg clutch species, and interpreted results within the framework of sibling...
In many species, territorial behavior is limited to the breeding season and is tightly coupled to circulating gonadal steroid levels. In contrast, both male and female red squirrels ( Tamiasciurus hudsonicus ) are highly aggressive in both the breeding and non-breeding seasons in defense of food...
The corticotropin-releasing hormone (CRH) plays a critical role in stress–response regulation in vertebrates. The activity of CRH depends on CRH-binding protein (CRH-BP). CRH-BP is considered to play a chaperoning role in stress. Limited information mainly from the insects is available on the...
Cytochrome P450 aromatase (CYP19) catalyzes conversion of testosterone to estrogen, and is thought to influence neural and reproductive development in vertebrates. Unlike higher vertebrates, many teleost fish, including the medaka ( Oryzias latipes ) have two aromatase genes, one expressed...
Angiopoietin-like protein 3 (ANGPTL3) is a 70 kDa secretory glycoprotein, which has been identified as a plasma triacylglycerol (TG)-increasing factor in KK/San mice. In this study, we have characterized the expression profile and activity of ANGPTL3 in the chicken, Gallus gallus . This is the...
Rana rugosa is unique among frog species in that it has two distinct types of sex chromosomes in two separate forms (XX/XY and ZZ/ZW). Treatment with sex steroids can reverse its gender from female to male or male to female. This phenomenon makes it a novel model for studying gonadal...
Episodic acidification resulting in increased acidity and inorganic aluminum (Al i ) is known to interfere with the parr-smolt transformation of Atlantic salmon ( Salmo salar ), and has been implicated as a possible cause of population decline. To determine the extent and mechanism(s) by which...
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