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An invitational expert meeting on indicators of prescribing quality was held on 13–15 May 2004, bringing together—from 19 European countries, the US, Canada, and Australia—40 researchers specialized in the development and application of indicators. The meeting was organized by the European...
In a group of elderly patients over 65 years of age with at least two cardiovascular diagnoses requiring chronic medication ( n =424), drug therapy at hospital discharge and at home thereafter was followed for a 1-year period. Two home visits took place at 3 months and 12 months after initial...
Erythromycin has a noticeable effect on the metabolism of quetiapine. When quetiapine is co-administered with CYP3A inhibitors such as erythromycin, the dosing regimen should be modified according to quetiapine TDM.
Treatment with S -omeprazole (esomeprazole; 20 mg and 40 mg) resulted in higher AUC values than with either R -omeprazole or racemic omeprazole after both single and repeated doses due to a lower metabolic rate of S -omeprazole than R -omeprazole and, consequently, racemic omeprazole. S...
Although the procedures adopted in the cases described in this review are uncommon, they potentially provide an alternative to the discontinuation of clozapine treatment in patients with complex symptomatologies for whom treatment with other antipsychotic medication is insufficient.
When renal failure had no impact on dosing, information was often missing. Such information is however important to differentiate, whether no dose adaptation is necessary or no information is available. If dose adjustment is required, application of a uniform concept is desirable.
The field of “Pharmacoepidemiology/Drug Utilization” research has been analysed by studying published research articles under the medical subject headings (MeSH terms) “Pharmacoepidemiology”, “Drug Utilization” and “Drug Utilization Review”. There were 1822 articles published, and...
We conclude that the pharmacokinetics and pharmacodynamics of felodipine were essentially unaltered by menthol.
This study is the first attempt to evaluate the frequency of potentially inappropriate medication use in the elderly French population. Female gender and low socio-economic characteristics reduced the chances of receiving optimal pharmacotherapy. The proportion of elderly subjects receiving...
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