Within the last year
Within the past 3 years
1 - 6 of 6 articles
Administration of caprine serum fraction–immunomodulator (CSF‐I) resulted in an enhanced survival rate in female Swiss Webster mice infected with approximately 5,000 colony‐forming units of Salmonella typhimurium. The prophylactic benefit of CSF‐I resulted in a significant reduction in...
Novel analogs of 1‐(N,O‐bis(5‐isoquinolinesulfonyl)‐N‐methyl‐L‐tyrosyl)‐4‐phenylpiperazine (KN‐62, 1) were synthesized and found to be potent antagonists in a functional assay, inhibition of ATP‐induced K+ efflux in HEK293 cells expressing recombinant human P2X7 receptors....
The therapeutic success of clozapine and other so‐called atypical antipsychotics has focused attention on the serotonin (5‐hydroxytryptamine; 5‐HT) system and its interaction with the dopaminergic system as a treatment for psychotic illnesses. Clozapine has been shown to display high...
Although anxiety is a major feature of ethanol withdrawal (EW) and much of treatment related to EW is focused on amelioration of the anxiety experienced during EW, less attention has been given to the anxiogenic effects of EW than to the convulsant effects. In this article, we review the animal...
Bioisosterism of the adenine and 8‐azaadenine nuclei was demonstrated by comparison of A1 adenosine receptor binding affinity of 2‐phenyl N6‐substituted adenines and the corresponding 8‐azaadenines. Some of these new compounds are very potent A1 adenosine receptor antagonists. This work...
Zonisamide (Zonegran®) is a broad‐spectrum antiepileptic agent that shares some pharmacological properties with other anticonvulsants, including phenytoin, carbamazepine, and valproic acid, but is differentiated from these agents by the ability to significantly block T‐type calcium channels....
Read and print from thousands of top scholarly journals.
Sign up with Facebook
Sign up with Google
Already have an account? Log in
Save this article to read later. You can see your Read Later on your DeepDyve homepage.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.