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In the present long-term, open-label study, the effects of policosanol (20 mg/d) were investigated in the treatment of type II hypercholesterolemia in patients with high global coronary risk. After dietary stabilization during a 5-week baseline period, 68 patients took policosanol 20 mg once...
In a prospective multicenter, randomized, double-masked trial, 30 patients with external otitis received betamethasone dipropionate in a 0.05% solution for 11 days. Fifty percent of the patients were assigned randomly to receive concomitant treatment with loratadine to help control itching, and...
This study investigated the effects of pravastatin and simvastatin in hypercholesterolemic patients with type 2 diabetes mellitus. Pravastatin and simvastatin were administered at the initial dosages approved in Japan (10 mg/d and 5 mg/d, respectively) to 40 patients using a crossover design....
The cerebrovascular and renal actions of antihypertensive agents are important clinically. The aim of the present study was to assess the effects of felodipine on cerebral blood flow (CBF) and renal blood flow (RBF) by a simple, noninvasive method for quantitative radionuclide angiography with...
A randomized, prospective, comparative, unmasked, 3-arm clinical trial was conducted to assess the efficacy of 2 short courses of ceftibuten in the treatment of uncomplicated cystitis. The study patients were ambulatory women ≥18 years of age with acute lower urinary tract infection...
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