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Unlike patients with either hypertension (HT) or angina pectoris (AP) alone, patients with both HT and AP usually have a reduced left ventricular compliance and may, therefore, have an impaired capability to cope with acute hemodynamic changes generated by standard beta-blockers or calcium...
The efficacy and tolerability of indeloxazine hydrochloride, a new nonanticholinergic antidepressant, were evaluated in 65 Korean patients with ischemic stroke 1 to 3 months after the occurrence of stroke. Thirty-two patients received an oral dose of indeloxazine 20 mg, three times daily, for 3...
Insulin sampled at various levels within several insulin preparation vials underwent high-performance liquid chromatography and fluorescence spectrophotometry to determine insulin content. Insulin content did not vary with Actrapid Human Insulin ® , Monotard Human Insulin ® , and Novolin N100...
Opioids, although effective postoperative analgesics, are associated with undesirable side effects. To determine whether nonopioid medication would reduce the amount required for postoperative analgesia, the efficacy of ketorolac, an injectable nonsteroidal anti-inflammatory drug, was studied in...
The angiotensin-converting enzyme (ACE) inhibitor enalapril was administered to 13 patients with chronic heart failure (New York Heart Association class II or III) for 12 weeks, and its effects on resting cardiac function (shown by echocardiogram), exercise capacity, and biochemical factors were...
The aim of this study was to obtain a conservative estimate of the current incidence of low serum cobalamin levels (cobalaminopenia) in a modern, postindustrial region in Sweden. All serum cobalamin determinations made during 1993 in one health care area (Umeå) with 131,393 inhabitants were...
In this double-masked, randomized, crossover, bioequivalence study, two 100-mg tablet preparations of sumatriptan (Suminat ® and Imigran ® ) were compared in 12 healthy male subjects (mean ± SD age, 25 ± 6 years). Pharmacokinetic variables—mean maximum plasma concentration, time to reach...
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