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Nucleic acids are polyanionic molecules that were historically considered to be solely surrounded by a shell of water molecules and a neutralizing cloud of monovalent and divalent cations. In this respect, recent experimental and theoretical reports demonstrate that water molecules within complex...
Multiprotein complexes are key players in virtually all important cellular processes. The past year has seen the publication of several papers that have illuminated what we know about the number and composition of these molecular machines, using high-throughput purification methods. Other studies...