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Regulation of epithelial tube size is critical for organ function. However, the mechanisms of tube size control remain poorly understood. In the Drosophila trachea, tube dimensions are regulated by a luminal extracellular matrix (ECM) (1–4) . ECM organization requires apical (luminal) secretion...
Many smaller and coastal states are keen to promote the environmental threat of climate change. Nigel Williams reports.
Does stress create mutations or only serve as an agent of natural selection? New experiments reveal effects of transcription and temperature on the response to growth limitation and could help resolve a 150-year-old debate.
Bacteria belonging to the genera Photorhabdus and Xenorhabdus participate in a trilateral symbiosis in which they enable their nematode hosts to parasitize insect larvae (1) . The bacteria switch from persisting peacefully in a nematode's digestive tract to a lifestyle in which pathways to...
Protesters became increasingly frustrated at the slow pace of developments at the UN's climate change conference in Copenhagen last month. Nigel Williams reports.
Accurate limb placement helps animals and robots to walk on substrates that are uneven or contain gaps. Visual information is important in controlling limb placement in walking mammals (1–4) but has received little attention in insects (5–7) . We investigated whether desert locusts walking...
Until recently, the literature on learning-related synaptic plasticity in invertebrates has been dominated by models assuming plasticity is mediated by presynaptic changes, whereas the vertebrate literature has been dominated by models assuming it is mediated by postsynaptic changes. Here I will...
New islands present the perfect opportunity for a species to get a fresh start and undergo adaptive radiation. For Galápagos land snails, both competition and resource diversity have together led to opportunity knocking twice.
Anchorage dependence of cell growth is a key metastasis-suppression mechanism that is mediated by effects of integrins on growth signaling pathways (1) . The small GTPase RalA is activated in metastatic cancers through multiple mechanisms and specifically induces anchorage independence (2–4) ....
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