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The amplitude and pitch fluctuations of natural soundscapes often exhibit “ 1/f spectra” (1, 2) , which means that large, abrupt changes in pitch or loudness occur proportionally less frequently in nature than gentle, gradual fluctuations. Furthermore, human listeners reportedly prefer 1/f...
Background Cell adhesion and motility are accomplished through a functional linkage of the extracellular matrix with the actin cytoskeleton via adhesion complexes composed of integrin receptors and associated proteins. To determine whether this linkage is attained actively or passively, we...
Cell division is regulated by protein kinases of the Cdk, Polo, and Aurora families (1) . Although it has long been established that temporal control is central to the coordinated action of these kinases, the importance of spatial regulation has only recently been appreciated and is still poorly...
The functional analysis of neuronal circuitry would be facilitated if researchers were able to control, over extended periods of time, the activity of genetically defined populations of neurons in vivo . New work using light-gated cation channels from green algae offers hope that this might soon...
Insect societies are paramount examples of cooperation, yet they also harbor internal conflicts whose resolution depends on the power of the opponents (1–4) . The male-haploid, female-diploid sex-determining system of ants causes workers to be more related to sisters than to brothers, whereas...
Background Previous studies have demonstrated reexpression of cell-cycle markers within postmitotic neurons in neurodegenerative tauopathies, including Alzheimer's disease (AD). However, the critical questions of whether cell-cycle activation is causal or epiphenomenal to tau-induced...
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