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This study investigated the long-term acceptability of a levonorgestrel-releasing intrauterine system (LNG-IUS) in 165 women after 6 and 36 months of use. Changes in menstrual bleeding pattern were experienced by 161 (98%) women, with a cessation or transient absence of menstruation occurring in...
Context Unintended pregnancies account for about half of all pregnancies in the United States and, in 1995, numbered nearly 3 million pregnancies. They pose appreciable medical, emotional, social and financial costs on women, their families and society. The US is not attaining national goals to...
The primary aim of this prospective 2-year follow-up study was to investigate the effect of depot medroxyprogesterone acetate (DMPA) on the maintenance of bone mass in women aged 30–45 years. The effects of estrogen or calcium substitution during the second year of follow-up was investigated in...
The follicle-stimulating hormone (FSH) binding inhibitor (FSHBI) has been identified as one of the factors present in follicular fluid exerting autocrine/paracrine effects on FSH actions in the ovary. Our group has isolated FSHBI from human ovarian follicular fluid and deduced its partial amino...
Norelgestromin (NGMN) and levonorgestrel (LNG) are the main active metabolites of norgestimate (NGM), but their relative contributions to the pharmacological effects of NGM are unclear. We have therefore determined the serum distribution of these NGM metabolites and assessed their steady-state...
As men play a prominent role in reproduction, it is therefore extremely useful to assess and encourage them to be involved in contraception, particularly in developing countries, where contraceptive goals have not been reached. This study was carried out in Kayseri, Turkey, in order to determine...
This double-blind randomized control study was conducted to evaluate whether a nonsteroidal anti-inflammatory drug (NSAID) could act as an effective pain control method during first trimester suction abortion, and whether co-treatment of NSAID with misoprostol will decrease the efficacy of the...
Accurate measurement of semen exposure resulting from condom failures can refine public health messages and improve predictions of condom efficacy in preventing pregnancy and HIV transmission. Eight hundred and thirty couples enrolled in a condom efficacy study were asked to collect a baseline...
The ability of cupric ions to immobilize human spermatozoa was assessed in vitro using an optical microscope. A Ringer’s solution containing human spermatozoa and three cupric ion concentrations of 8 × 10 −8 mol/L, 8 × 10 −6 mol/L and 8 × 10 −5 mol/L were tested. The higher cupric ion...
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