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The overall number of deaths from cancer is increasing. The absolute magnitude of this increase is in debate. Unfortunately, we are unable to estimate the interactions between two or more agents such as cigarettes and asbestos. None of the appropriate studies is precisely able to know the exact...
The mechanisms of carcinogenesis are just beginning to be understood. There is recent interest in the broad classification of carcinogens into two categories based upon their mechanism of action: those that interact with DNA via a genetic mechanism are termed genetic carcinogens; and those that...
Maintaining an awareness that workplace factors may contribute to occupational cancer is one of the most formidable obstacles in early clinical recognition. This early recognition provides an opportunity for a practicing physician to make an important contribution to new knowledge in the field....
Epidemiology attempts to establish a quantitative causality which is essential in preventive medicine strategies for occupational cancer. By studying carefully exposure effect relationships and populations at risk, subtle causes of occupational cancer can be identified. The nature of...
The contribution of occupational and environmental exposures to the etiology of cancer is a topic of considerable scientific and public interest. If an occupational environmental exposure is associated with cancer in man, then both the exposure and the disease are preventable by appropriate...
The scientific understanding of cancer and degenerative disease is being aided by new methodologies which are now used to approach the problem of environmental and occupational carcinogens and anticarcinogens. This paper reviews these powerful new tools and relates them to “;natural” mutagens...
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