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There is extensive evidence that Moyamoya disease has a tendency for multifactorial inheritance, although the pathogenesis of Moyamoya disease is not clear. The authors report five cases showing familial occurrence of Moyamoya disease and analyse its clinical characteristics. In the past 15...
To determine the difference in cerebral hemodynamics between Moyamoya disease and atherosclerotic occlusion of the major cerebral arterial trunks, we measured local cerebral blood flow (CBF) and local CO 2 reactivity (CO 2 R) by xenon-enhanced computed tomography (CT). A total of 11 adult...
We recently treated children with Moyamoya disease using a fronto-temporo-parietal combined indirect bypass procedure. Three different indirect bypass procedures (frontal EMAS, EDAS, EMS) were simultaneously carried out at three different sites. We thus treated 16 sides in 12 pediatric patients...
In this study, measurement of Epstein-Barr virus (EBV) and cytomegalovirus (CMV) viral antibody titers and analysis of both viral genomic sequences using polymerase chain reaction (PCR) were performed to clarify the correlation of viral infection and Moyamoya disease. Serum samples were obtained...
Over a period of 22 years, 31 Moyamoya cases have been recorded in Yugoslavia. In this group of the patients comprising four children and 27 adults, peak age incidence is in the third and fourth decades of life. Males and females have been almost equally affected. Familial cases or territorial...
Moyamoya disease is a progressive stenoocclusive disease at the terminal portion of the bilateral internal carotid arteries. An unusual vascular network is formed as a result of ishemic change of cerebrovascular system. Although some investigations suggested possible etiological factors of...
We studied the cerebral blood flow (CBF), cerebrovascular response to hypercapnia, oxygen extraction fraction (OEF), metabolic rate for oxygen (CMRO 2 ), blood volume (CBV) and transit time (TT: CBV/CBF) in Moyamoya disease using positron emission tomography (PET). The subjects consisted of 23...
Two topics concerning the leptomeningeal vessels are discussed. The first portion indirectly proves that angiographic `vault Moyamoya' consists of dilated preexisted vessels rather than newly-formed vessels, using morphometric analysis. The second portion presents a 67 year old autopsied case...
To both clarify the current clinico-epidemiological features of Moyamoya disease in Korea as well as compare these cases with Japanese patients, 451 cases were collected from 26 Korean major neurosurgical institutes and 296 definite cases were analyzed statistically. Although the Korean age...
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