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Changes in the deoxyribonucleotide pools following a single oral administration of 13 mglkg of 5-fluorouracil (5-FU) or of 64.8 mglkg of UFT (a mixed compound of tegafur and uracil) were investigated. We compared their pharmacodynamics and effects on nucleotide metabolism in L1210 ascites tumor...
Forty-seven patients with poor-prognosis myeloid leukemias received induction therapy with high-dose cytosine arabinoside (HDara-C), 1.5–3.0g/m 2 for 8–10 doses, and mitoxantrone (DHAD), 12–15 mglm 2 for 3 doses. Complete remissions were achieved in 21 (45%, 95% confidence interval (CI)...
The patient requiring ostomy surgery has needs above and beyond the typical perioperative needs of an individual experiencing major abdominal surgery. These needs may be categorized as technical ostomy management, information, and emotional support. The health care team managing ostomy patients...
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