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Evidence of improvements in outcomes gained by aggressive treatment of hypertension, hyperglycaemia and Edyslipidaemia in type 2 diabetic patients has encouraged the setting of ambitious targets for risk factor control. The therapeutic regimens needed to achieve tight control results in...
The modern general practitioner is able to examine and audit his practice diabetes population in great detail because of extensive computerisation and Read-coding. The ability to compare one practice statistics with another brings with it added pressures to be seen to achieve certain standards....
Lifestyle intervention prevents or delays the conversion from impaired glucose tolerance (IGT) to type 2 diabetes. However, many subjects fail to achieve and/or maintain long-term weight loss and to follow a regular exercise regimen may require pharmacologic therapy. Insulin resistance in liver,...
It is well established that the incidences of type 2 diabetes and impaired glucose tolerance are very low at ideal body weight (body mass index BMI 21—22 kg/m 2 ) but increases with increasing body fat and BMI. Adipose tissue is an active endocrine organ which secretes many hormones involved in...
Obesity, diabetes and glycaemic control are inter-linked. Weight gain is associated with worsening diabetic control and can be exacerbated by therapies aimed at controlling hyperglycaemia. Auditing our practice in a district general hospital, we have examined our diabetic population with regards...
The prevalence of diabetes is increasing worldwide, bringing personal and economic burdens. Impaired glucose tolerance (IGT) generally precedes type 2 diabetes and strategies which target IGT and delay or prevent the onset of type 2 diabetes are being explored. IGT and type 2 diabetes are...
Physical activity improves insulin sensitivity and glucose metabolism, although such effects are short-lasting and regular exercise is needed to sustain them. Weight loss, especially loss of visceral fat, appears to be especially important in improving metabolic function and clinical outcomes....
The substantial burden of morbidity and mortality associated with type 2 diabetes and the high costs associated with the management of diabetic complications highlight the need for the development of strategies for the prevention of diabetes. Impaired glucose tolerance is a pre-diabetic state...
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