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The effect of soleus activation on the soleus H-reflex was investigated during controlled lengthening and shortening of the plantar flexor muscles. Maximal H-reflexes and M-waves were evoked at the same muscle length (ankle angle 90°) during lengthening and shortening (ankle angular velocity 5°...
Adenosine (ADO) has an important role in the ischemic brain as an endogenous neuroprotective factor. On the other hand, intraischemic hypothermia ameliorates ischemic neuronal injury. To investigate the effect of ADO during intraischemic mild hypothermia, the extracellular concentration of ADO,...
The purpose of this study was to identify brain sites that contribute to the Δ 9 -tetrahydrocannabinol (Δ 9 -THC)-induced impairment of spatial memory in rats. Rats were tested in the eight-arm radial maze after microinjections of Δ 9 -THC into one of 14 different brain regions. The bilateral...
Many experimental studies suggest that NFκB, a transcription factor involved in acute inflammation, and cytokines participate in neuronal excitability and/or glial scar formation in epilepsy. In this report, we looked for the expression of NFκB in hippocampi surgically removed in patients with...
The aim of this study was to examine the effects of one eye enucleation on the expression of c-Fos protein in the hypothalamus of the Japanese monkey ( Macaca fuscata ). Compared with an intact monkey, significantly increased numbers of c-Fos positive neurons were observed in the supraoptic...
The effects of cyclic AMP (cAMP)-related compounds on in vivo ( 3 H)SCH 23390 binding to striatal dopamine D 1 receptors were investigated using autoradiography in order to clarify the possible regulation of the cAMP-dependent mechanisms in the in vivo ligand–receptor bindings in the living...
To investigate the role of transglutaminase (TG) in the pathophysiology of dentatorubral-pallidoluysian atrophy (DRPLA), the distributions of ubiquitin-positive neuronal intranuclear inclusions (Ub-NII) and TG activity were studied in three patients with DRPLA and four disease controls. In the...
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