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In the treatment of atherosclerosis, therapeutic angioplasty is commonly used to restore normal blood flow in stenosed arteries. This procedure, however, is associated with vascular endothelial cell erosion (denudation) of the intimal lining and subsequent acute arterial closure through...
A new platform of hypothermic solutions, the HypoThermosol® (HTS) series, has been developed for the improved hypothermic storage of cells, tissues, and organs. Cells and tissues cold-stored in HTS-FRS demonstrate improved viability when returned to normothermic temperatures in comparison with...
The objective of this study was to develop a reliable, low-cost, and practical directional solidification device (DSD) for cryopreservation of biological cells and tissues. In this study, a linear temperature distribution was established in an aluminum block between a higher temperature source (...
Frozen cells are known to be unstable at elevated subzero temperatures; however, the kinetics of cell damage as a function of storage temperature and time are not well understood. The present study investigated the instability of frozen human erythrocytes during isothermal storage at elevated...
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