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We investigated the utility of 1,6-hexamethylene diamine (HDA) hemoglobin adducts as biomarkers of exposure to 1,6-hexamethylene diisocyanate (HDI) monomer. Blood samples from 15 spray painters applying HDI-containing paint were analyzed for hemoglobin HDA (HDA-Hb) and N -acetyl-1,6-hexamethylene...
Objective : XRCC4 play a key role in nonhomologous end-joining repair pathway. Alterations in DNA repair gene have been shown to reduce DNA repair capacity thereby inflicting carcinogenesis. Methods : In a hospital-based case-control study, 192 prostate cancer (PCa) and 224 healthy controls. They...
The purpose of this paper is to identify immunologic hallmarks of excessive bodyweight. The analysis is based on 176 adults (106 women, 70 men) who participated in a nested case-control study in Italy. All participants were healthy at the time of blood collection and aged between 36 and 75 years....
Background : MRproADM and MRproANP can be used as diagnostic and prognostic markers in heart failure. Aim : The objective was to identify confounding factors for the interpretation of plasma MRproADM and MRproANP concentrations. Methods : A total of 518 healthy volunteers with a mean age of 60.84...
Context : The validity of urinary correction standards has not been established for most analytes. Methods: We compared urinary creatinine and specific gravity as dilution correction standards for cotinine in a community-based study of smokers. Results : Models of blood cotinine regressed against...