New! You can now keep track of new articles from Biological Chemistry on your personalized homepage!
Abstract The process of muscle regeneration in normal and dystrophic muscle depends on locally produced cytokines and growth factors and requires the activity of the urokinase plasminogen activator/urokinase plasminogen activator receptor/plasminogen activator inhibitor-1 system. In this study we...
Abstract Plasminogen activators of the urokinase and tissuetype and fetal calf serum (uPA, tPA, FCS) exert their mitogenic effect on quiescent human dermal fibroblasts and modulate the mRNA expression of cellcycle related genes. The present study deals with the effects of PAs on the expression of...
Abstract The plasminogen activating system is important for extracellular proteolysis and plays a regulatory role in interactions with other tissue degrading systems. Studies on the plasminogen activating system in gingival crevicular fluid (GCF) as well as gingival tissue are reviewed. tPA, uPA,...
Abstract We have recently identified a gene (the WFIKKN gene) on human chromosome 16 (16p13.3) that encodes a secreted protein containing WAPtype, Follistatin/ Kazal type, Kunitztype and NTRtype proteaseinhibitory modules and an Immunoglobulin domain (Trexler et al., Proc. Natl. Acad. Sci. USA 98...