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Bcl-2 family members are central to the control of cell survival. Work of the last years has established that the function of these proteins can be regulated by mitogenic signaling cascades. Within the scope of this review, we will discuss the contribution of Bcl-2-dependent signaling pathways to...
Apoptosis plays an important role during development and in the maintenance of multicellular organisms. Bcl-2 family members affect cell death in either a positive or negative fashion. Although some redundancy exists between family members, expression of certain family members is important during...