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Highlights ► Arginine is the precursor to nitric oxide and is a conditionally essential amino acid. ► We examined behavioral effects of dietary arginine depletion during development and adulthood. ► Dietary arginine depletion reduced depressive-like responses in male but not female mice....
Highlights ► Acquisition of a spatial working memory task without prior habituation. ► Determination of difference between strains in baseline level of anxiety. ► Difference between strains of mice in the acquisition of a working memory task. ► Assessment of anxiety and memory within the...
Highlights ► Hippocampal β-catenin of Black Swiss (BS) mice is lower in comparison with other strains. ► No differences were found in the frontal cortex. No Differences were found for BDNF expression in hippocampus or frontal cortex. ► Risperidone ameliorated amphetamine-induced...
Highlights ► Early postnatal administration of a vaccine preservative, thimerosal, produces persistent neurobehavioral alteration in rats and changes in brain dopamine system. ► Mostly locomotor, emotional and social behaviors are affected. ► Spatial memory is not affected. ► The changes...
Highlights ► We established a correlation between these tests and morphological data for brain injury. ► The fact that our methods of estimating infract size produces reliable and well correlated results at 24 h is of great clinical significance. ► Most treatment modalities for ischemic...
Highlights ► Performance in a manual stimulus-response compatibility task is impaired in schizophrenia. ► Executive control deficits seen in anti-saccades generalize to manual motor control. ► Neuropsychological deficits are particularly evident in complex, multi-component tasks.
Highlights ► SHR shifted to the right the function relating adjunctive drinking to inter-food interval length. ► Adjunctive drinking was lower for WKY than SHR and Wistar rats at any inter-food interval value. ► Licking was more persistent in SHR than in the other rats at long inter-food...
Graphical abstract . Time schedule of animal experiments. Animals were tested by apomorphine-induced rotational and elevated body swing test (EBST) tests at 3 times before application of the blockers: Before the injection of the 6-hydroxydopamine (6-OHDA) and in the 2nd and 3rd weeks...
Highlights ► Synesthetes automatically associate color with letters, numbers, weekdays, or months. ► This perceptual experience may be caused by neural hyperconnectivity. ► We aim to find the gene(s) responsible for this type of neural crosstalk. ► Our results suggest that colored...
Highlights ► DRD2/ANKK1 Taq I A polymorphism affects corticostriatal activity. ► Higher signal intensity in the homozygous group than in the heterozygous group. ► The molecular heterosis may play an important role in these responses.
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