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Serotonin (5-HT) receptor 2A (5-HT 2A ) and 2C (5-HT 2C ) agonists have been reported to facilitate female rat lordosis behaviour. This study investigated the acute effects of the 5-HT 2A receptor agonist DOI ((±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane) and the 5-HT 2C receptor agonist...
The prenatal methylazoxymethanol acetate (MAM) treatment has been proposed as a suitable model for the neurodevelopmental aspects of schizophrenia since the morphological abnormalities it induces in the brain are subtle and in line with most reports of neuropathology in schizophrenic brains....
Early detection of progressive diseases such as Alzheimer’s Disease (AD) is crucial for both the treatment and study of the disease. Performance on a visuo-spatial paired-associates learning (vsPAL) task was recently shown to reliably predict a diagnosis of AD in aged populations. The present...
The aim of the present study was to measure visual acuity (VA) by the sweep visual evoked potential method (sVEP) and relate it to the degree of motor impairment in children with spastic cerebral palsy (SCP). Monocular VA was estimated in 37 SCP children aged from 6 to 48 months, classified as...
Attention-deficit/hyperactivity disorder (ADHD) is a disorder affecting between 2 and 12% of grade-school children disturbing social, academic, and occupational functioning. Problems related to social adjustment and functioning and/or psychiatric problems will exist in 50–70% of adolescents and...
Our previous work has shown that normal male Wistar rats can differ systematically in their behavioral response to the elevated plus-maze (EPM), where animals with high (HA) or low anxiety (LA) levels can be identified based on the percentage of time spent in the open arms. These animals also...
The effects of the P2 receptor ligands 2-methylthio ATP (2-MeSATP; 10 pmol)—as a non-specific agonist—and pyridoxalphosphate-6-azophenyl-2′,4′-disulphonic acid (PPADS; 10 pmol)—as a non-selective antagonist—after bilateral intra-accumbens injection on the locomotor response were...
Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated...
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