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A study is presented which describes the adsorption in vitro of albumin and fibrinogen onto a minishunt oxygenation unit. The unit is characterized by flow through 10 etched microchannel conduíts with a mícroporous membrane placed across the diametric plane of the channel for gas exchange. The...
A feasibility study on developing an implantable, biodegradable insulin delivery system was carried out. Insulin-albumin microbeads (50–1,000 μm diameter) were implanted in diabetic rats. After a single subcutaneous implant of the glutaraldehyde crosslinked microbeads, elevated blood-insulin...
The development and properties of a novel adsorbent system consisting of polyacrolein microspheres encapsulated in agarose is described. In the model system, the microspheres contain covalently bound bovine serum albumin. In practice any protein or ligands with primary amino groups may be...
Following reports of the successful use of chemically processed human umbilical veins as medium and small diameter arterial substitutes, the development of new and improved techniques for the preparation, fixation and storage of these bioprostheses has been attempted. A series of physical and...
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