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Total knee arthroplasty (TKA) has proven to be a highly successful and reproducible intervention for patients with disabling arthritis of the knee that is refractory to nonoperative management.1,2 More than 500 000 TKA procedures are performed annually in the United States, and that number is...
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Frequency of Failure to Inform Patients of Clinically Significant Outpatient Test Results Casalino et al found that physicians frequently fail to inform patients of important abnormal test results. They reviewed outpatient medical records of 5434 patients in 23 medical practices and found...
Postmarketing surveillance and the determination of the real-world safety profile of prescription drugs is arguably flawed. Recent identification of significant adverse effects associated with newly approved prescription drugs support the sometimes-held view that a new system needs to be...
The Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment (ExTRACT)–Thrombolysis in Myocardial Infarction (TIMI)-25 study1 demonstrated that the administration of enoxaparin sodium, 30 mg intravenously, followed by subcutaneous injections of 1 mg/kg twice daily (dose...
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