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Abstract • Hemodialysis with a low-bicarbonate dialysate was used in four patients for the simultaneous treatment of acute renal failure and fluid overload associated with alkalemia. All patients had a mixed acid-base disorder, namely respiratory alkalosis superimposed on metabolic alkalosis....
Abstract • Of 41 patients with Klebsiella bacteremia studied, most were newborn or elderly and only one patient had community-acquired infection. The incidence of bacteremia was evenly distributed over 16 months, except that infections in the newborns occurred in a cluster. The initial site of...
Abstract Amphotericin B is a polyene antibiotic widely used in the therapy of systemic fungal infections. Recently, experimental evidence has indicated that in addition to increasing membrane permeability,1 amphotericin B is an immunostimulant.2 Both of these effects have been exploited to...
Abstract • Profound hypercalcemia can impose both diagnostic and therapeutic difficulties. First, profound hypercalcemia can be life-threatening as well as difficult to control. Second, the use of mithramycin in the treatment of severe hypercalcemia is emphasized. Third, hypercalcemia of...
Abstract The article by Cello et al in this issue (see p 501) emphasizes two messages: (1) that patients with a history of acid or lye ingestion should undergo early fiberoptic esophagoscopy and gastroscopy because the procedures are safe and delineate the extent of injury; and (2) that many...
Abstract • Since two thirds of the studies appearing in the best medical journals contain unwarranted conclusions, it is important for the physician to be aware of pitfalls. Two common errors are committed; the first consists of confusing statistical significance with medical significance, and...
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