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The neurotoxic effect of chronic exposure to low-level lead (Pb) with advancing age is becoming an important social issue of public health. To examine the effects of low-level Pb treatment on behavior, cognition and brain energy metabolism in aging, we administered 200 ppm Pb acetate to adult...
The objectives of this study were to describe a population of elderly patients at the beginning of their rehabilitation period as regards subjective well-being and dependence in activities of daily living (ADL). In a Swedish rural county 244 patients aged 65+ who had begun rehabilitation within...
The present work was designed to study the effect of aging on some parameters of the glutamatergic, aminergic and cholinergic neurotransmission, in the main brain areas of mice of the long-surviving BALB/c-nu strain. We have assayed: (1) the density of three ionotropic receptors for excitatory...
The aims of this study were to compare the clinical features of patients with pulmonary embolism (PE) and patients in whom the initial suspected diagnosis was not confirmed by the complementary studies and to determine the possible clinical differences among patients with PE according to age. A...
In 1996 the National Institute for Longevity Sciences (NILS) started an aging/aged farm (Aging Farm), an animal farm for producing aging/aged laboratory rodents on inbred strains, F344/N rats and C57BL/6 mice at its Experimental Animal Facility Wing, based on plans prepared by the Laboratory...
The use of β -blockers after myocardial infarction was investigated in 100 patients (age range 30–89 years), from January to December 1997, in Caerphilly District Miner’s Hospital. Out of 54 patients eligible for β -blockers only 27 (27/54 (50%)) patients received such therapy. We conclude...
The scope of this study was to evaluate the prevalence of comorbidity in elderly subjects with neoplastic diseases, and to compare it to those without tumor pathologies. Three groups of patients have been considered: (A) 35 elderly oncological patients; (B) 38 young/adult oncological patients;...
A total 325 patients were studied at admission for myocardial infarction, measuring plasma fibrinogen (FBG), creatine phosphokinase (CPK) and lactate dehydrogenase (LDH) and automatized hemocromocytometric parameters in order to contribute to explain the excess mortality reported in very elderly...
Socio-demographic, anthropometric assessment, dietary pattern, lifestyle of 384 Thai elderly (55 males and 329 females) aged 60–94 years, who were members of an informal social activity group, were investigated. The 3-day dietary record was determined with the help of food models by random...
The aim of this study has been to identify changes of 24-h blood pressure variability, as related to age and sex in hypertensive subjects. As regards this point several international studies have shown the increase of morbidity and mortality caused by cardiovascular diseases in postmenopausal...
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