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Introduction: Prediction models of most toxicological assays translate continuous data to binary classifications (“positive” or “negative”) using cutoff values. Mostly these cutoffs do not consider data variability. Some OECD test guidelines, however, provide a range close to the cutoff. If a...
Introduction: German chamomile is a botanical ingredient commonly used in cosmetics, thus determination of skin sensitization effects of German chamomile constituents is critical for the safety of consumers. Nonetheless, a systematic investigation of skin sensitization potential of chamomile...
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