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EPR spectroscopy can give biologically important information, such as tissue redox status, pO 2 , pH, and microviscosity, based on variation of EPR spectral characteristics ( i.e. , intensity, linewidth, hyperfine splitting, and spectral shape of free radical probes. EPR imaging (EPRI) can obtain...
Tumor hypoxia is related to tumor progression and therapy resistance, which leads to poor patient outcome. It has been suggested that measuring the hypoxic status of a tumor helps to predict patient outcome and to select more targeted treatment. However, current methods using needle electrodes or...