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PURPOSE: To apply stroke subclassification criteria based on computer tomography (CT) to strokes in the Nurses' Health Study and to assess reliability and validity of the criteria. METHODS: Among 121,701 women aged 30–55 years at entry, subclassification criteria were applied to 1369 incident...
PURPOSE: Whether various vitamins and carotenoids can protect against ischemic heart disease remains an unsettled question. METHODS: We performed a cross-sectional analysis of data from National Health and Nutrition Examination Survey III (1988–1994) and examined the associations between serum...
PURPOSE: Lifetime and age-conditional probability (risk) estimates of developing lung cancer in the United States are presented by age, race, and gender. Effects on the risk estimates of an aging population and changing tobacco use are identified. METHODS: Risk estimates were derived by applying...
PURPOSE: To investigate the impact on subject response of an information brochure and cash incentives included with mailed questionnaires in case-control studies. METHODS: A randomized trial was carried out within a case-control study investigating cancer in the Province of Ontario. Brochures...
PURPOSE: Whereas prison inmates are reported to exhibit poorer overall health status and higher rates of health care utilization than the general population, no current information exists on the overall disease profile of the U.S. prison population. The present study examined the prevalence of...
PURPOSE: To assess the balance of benefits and risks of supplementation with beta-carotene, vitamin E, vitamin C, and multivitamins on cancer, cardiovascular (CVD), and eye diseases. DESIGN: Physicians' Health Study II (PHS II) is a randomized, double-blind, placebo-controlled trial enrolling...
PURPOSE: We updated an earlier study in this community from 1945–1974 in order to assess trends in the incidence of, risk factors for, and survival from endometrial cancer in 1975–1991. METHODS: Incidence rates were based on all new cases of endometrial cancer diagnosed among Olmsted County,...
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