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The volume and composition of the gastric contents as well as the rates of gastric emptying and secretion were determined simultaneously in conscious chair-adapted monkeys. These determinations were made during fasting and after a liquid meal, thereby allowing studies of the physiologic variables...
In vivo, vasoactive intestinal peptide (VIP) produces simultaneous increases in blood glucose and insulin levels. In order to determine whether VIP, like its homologues, also stimulates insulin secretion directly, studies were made in controlled glucose media employing the vascularly perfused cat...
Turnover rates of blood glucose and lactate, along with the rates of their interconversion, were calculated from changes of their specific activities in rats infused with U-14C glucose and U-14C lactate based on a simple flux model of the Cori cycle. In the fasted state, most (75%) of the glucose...
Previous studies have shown that anterior hypothalamic deafferentation in rats completely suppresses the increase in plasma free fatty acid (FFA), but not the hyperglycemia induced by administration of 2-deoxyglucose, suggesting a specific central regulation of FFA mobilization. The physiological...