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An alternative formulation of direct methods for phase refinement using the sign probability originally introduced for breaking the phase ambiguity intrinsic in single isomorphous replacement or single-wavelength anomalous diffraction data has been proposed. This formulation can incorporate known...
Shank proteins are a new family of scaffold proteins interacting with various membrane and cytoplasmic proteins. Shank contains multiple protein-protein interaction sites, including ankyrin repeats, an SH3 domain, a PDZ domain, a long proline-rich region and an SAM domain. The PDZ domain of Shank...