Differential Cognitive Response to a Mood Challenge Following Successful Cognitive Therapy or Pharmacotherapy for Unipolar DepressionSegal, Zindel V.; Gemar, Michael; Williams, Susan
doi: 10.1037/0021-843X.108.1.3pmid: N/A
This study examined the nature of cognitive reactivity to mood changes in formerly depressed patients. Patients who recovered either through cognitive–behavior therapy (CBT; N = 25) or through pharmacotherapy (PT; N = 29) completed self-reported ratings of dysfunctional attitudes before and after a negative mood induction procedure. In response to similar levels of induced sad mood, PT patients showed a significant increase in dysfunctional cognitions compared with patients in the CBT group. To evaluate the effects of such cognitive reactivity on the subsequent course of depression, follow-up analyses reassessed 30 patients several years after initial testing. Results indicated that patients’ reactions to the mood induction procedure were predictive of depressive relapse. These findings argue for differential effects of treatment on cognitive reactivity to mood induction and for the link between such reactivity and risk for later depressive relapse.
Drug-Abusing Patients and Their Intimate Partners: Dyadic Adjustment, Relationship Stability, and Substance UseFals-Stewart, William; Birchler, Gary R.; O’Farrell, Timothy J.
doi: 10.1037/0021-843X.108.1.11pmid: N/A
The dyadic adjustment and substance use of couples with a drug-abusing husband (n = 94), couples with a drug-abusing wife (n = 36), couples in which both partners abused drugs (n = 87), and non-substance-abusing conflicted couples (n = 70) were examined. For couples with 1 drug-abusing partner, a higher percentage of days abstinent during the year before treatment for drug abuse was associated with a higher level of relationship satisfaction. When both partners abused drugs, the relationship between percentage of days abstinent and relationship satisfaction became stronger and more negative as the time partners spent together using drugs increased. A higher percentage of days abstinent was associated with relationship stability for couples with 1 drug-abusing partner during and 1 year after treatment; for couples in which both partners abused drugs, a higher percentage of days abstinent was associated with relationship instability.
Spatial Frequency Masking in Positive- and Negative-Symptom SchizophreniaSlaghuis, Walter L.; Curran, Charles E.
doi: 10.1037/0021-843X.108.1.42pmid: N/A
The role of transient and sustained channels in masking was investigated in groups with positive and negative symptoms in schizophrenia and in a control group. The target stimulus was a 3.0 c/deg sinusoidal grating, which was masked at 11 stimulus-onset asynchronies between −40 to 360 ms by a 1.0 c/deg mask or an 11.0 c/deg mask. The results showed that there was no difference between the control and positive-symptom groups in the perception of the 3 c/deg target stimulus, nor was there a difference when the target was masked by 1 or 11 c/deg masking stimuli. In comparison with the control and positive-symptom groups, the negative-symptom group showed a significantly higher threshold for the perception of the 3 c/deg target stimulus and more masking with a 1 c/deg mask, but not with an 11 c/deg mask. The results provide evidence for distinguishable differences in visual masking between groups with positive and negative symptoms in schizophrenia.
The Relationship Between Personality Pathology and Dysfunctional Cognitions in Previously Depressed AdultsIlardi, Stephen S.; Craighead, W. Edward
doi: 10.1037/0021-843X.108.1.51pmid: N/A
Multivariate and univariate regression models were used to examine the relationship between Axis II personality pathology and dysfunctional cognitions in a follow-up study of 40 formerly depressed inpatients. A dimensionalized measure of overall Axis II pathology was significantly and positively related to dysfunctional attitudes (Dysfunctional Attitudes Scale [DAS]) and maladaptive negative event attributions (Attributional Style Questionnaire–Negative Composite [ASQ-N]); the Axis II measure accounted for approximately 29% of the variance in DAS and 14% of the variance in ASQ-N, after controlling statistically for subsyndromal depressive symptoms (Beck Depression Inventory [BDI]). Axis II pathology was not significantly associated with positive event attributions, and no significant Axis II × BDI interaction effects were observed. A secondary canonical analysis of Axis II clusters was largely consistent with a hypothesized general personality pathology factor associated with dysfunctional cognitions, though a more specific association between Axis II Cluster C pathology and dysfunctional attitudes was also observed.
Psychopathy Across Cultures: North America and Scotland ComparedCooke, David J.; Michie, Christine
doi: 10.1037/0021-843X.108.1.58pmid: N/A
Differences in the prevalence and presentation of psychopathic personality disorder between North America and Scotland were evaluated. R. D. Hare’s (1991) Psychopathy Checklist—Revised ratings obtained from a sample of 2,067 North American male prisoners and forensic patients were compared with ratings obtained from 246 Scottish male prisoners. Item response theory methods were used to examine differences in the performance of items and to equate the scale across settings. The items had equal relevance to the description of psychopathic personality disorder in both settings; however, the Scottish prisoners had to have higher levels of the underlying latent trait before certain characteristics became apparent. The prevalence of the disorder appears to be lower in Scotland. Explanations for the observed differences in terms of enculturation, socialization, and migration are explored.
Normal Time Course of Auditory Recognition in Schizophrenia, Despite Impaired Precision of the Auditory Sensory (“Echoic”) Memory CodeMarch, Lucy; Cienfuegos, Angel; Goldbloom, Lyra; Ritter, Walter; Cowan, Nelson; Javitt, Daniel C.
doi: 10.1037/0021-843X.108.1.69pmid: N/A
Prior studies have demonstrated impaired precision of processing within the auditory sensory memory (ASM) system in schizophrenia. This study used auditory backward masking to evaluate the degree to which such deficits resulted from impaired overall precision versus premature decay of information within the short-term auditory store. ASM performance was evaluated in 14 schizophrenic participants and 16 controls. Schizophrenic participants were severely impaired in their ability to match tones following delay. However, when no-mask performance was equated across participants, schizophrenic participants were no more susceptible to the effects of backward maskers than were controls. Thus, despite impaired precision of ASM performance, schizophrenic participants showed no deficits in the time course over which short-term representations could be used within the ASM system.
Effects of Methylphenidate on Complex Cognitive Processing in Attention-Deficit Hyperactivity DisorderBerman, Tamara; Douglas, Virginia I.; Barr, Ronald G.
doi: 10.1037/0021-843X.108.1.90pmid: 10066996
Three experiments were conducted to explore the effects of methylphenidate (MPH), attention-deficit hyperactivity disorder (ADHD) diagnosis, and age on performance on a complex visual-memory search task. Results showed that the effects of MPH varied with information load. On low-processing loads, all doses of MPH helped children with ADHD to improve accuracy with no cost to reaction time (RT), whereas on high loads, higher MPH doses improved error rates while slowing RT. Without medication, children with ADHD showed high error rates and slow RTs across both low and high loads, as did younger, normal control children. Because MPH slowed performance on only the most difficult, high-load conditions, it is argued that the drug improves self-regulatory ability, enabling children with ADHD to adapt differentially to high and low loads.
A Longitudinal Study of Children of Alcoholics: Predicting Young Adult Substance Use Disorders, Anxiety, and DepressionChassin, Laurie; Pitts, Steven C.; DeLucia, Christian; Todd, Michael
doi: 10.1037/0021-843X.108.1.106pmid: N/A
This study tested the specificity of parent alcoholism effects on young adult alcohol and drug abuse/dependence, anxiety, and depression, and tested whether adolescent symptomatology and substance use mediated parent alcoholism effects. Participants were from a longitudinal study in which a target child was assessed in adolescence and young adulthood with structured interview measures (N = 454 families at Time 1). Results showed unique effects of parent alcoholism on young adult substance abuse/dependence diagnoses over and above the effects of other parental psychopathology. There was some evidence of parent alcoholism effects on young adult depression and of maternal alcoholism effects on young adult anxiety, although these were not found consistently across subsamples. Mediational models suggested that parent alcoholism effects could be partially (but not totally) explained by adolescent externalizing symptoms.
Context-Processing Deficits in Schizophrenia: Converging Evidence From Three Theoretically Motivated Cognitive TasksCohen, Jonathan D.; Barch, Deanna M.; Carter, Cameron; Servan-Schreiber, David
doi: 10.1037/0021-843X.108.1.120pmid: N/A
To test the hypothesis that the ability to actively represent and maintain context information is a central function of working memory and that a disturbance in this function contributes to cognitive deficits in schizophrenia, the authors modified 3 tasks—the AX version of the Continuous Performance Test, Stroop, and a lexical disambiguation task—and administered them to patients with schizophrenia as well as to depressed and healthy controls. The results suggest an accentuation of deficits in patients with schizophrenia in context-sensitive conditions and cross-task correlations of performance in these conditions. However, the results do not definitively eliminate the possibility of a generalized deficit. The significance of these findings is discussed with regard to the specificity of deficits in schizophrenia and the hypothesis concerning the neural and cognitive mechanisms that underlie these deficits.
Fear-Potentiated Startle Conditioning to Explicit and Contextual Cues in Gulf War Veterans With Posttraumatic Stress DisorderGrillon, Christian; Morgan, Charles A.
doi: 10.1037/0021-843X.108.1.134pmid: N/A
Aversive conditioning to explicit and contextual cues was examined in Gulf War veterans with and without posttraumatic stress disorder (PTSD) by use of the startle reflex methodology. Veterans participated in a differential aversive conditioning experiment consisting of 2 sessions separated by 4 or 5 days. Each session comprised two startle habituation periods, a preconditioning phase, a conditioning phase, and a postconditioning extinction test. In contrast to the non-PTSD group, the PTSD group showed a lack of differential startle response in the presence of a conditioned stimulus with or without an unconditioned stimulus in Session 1 and an increase in the baseline startle response during Session 2. The PTSD group also exhibited normal differential conditioning following reconditioning in Session 2. These data suggest that individuals with PTSD tend to generalize fear across stimuli and are sensitized by stress.